2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanoic acid
Fmoc-2-aminoheptanoic acid
CAS: 1219184-45-8
Molecular Formula: C22H25NO4
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanoic acid - Names and Identifiers
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanoic acid - Physico-chemical Properties
| Molecular Formula | C22H25NO4 |
| Molar Mass | 367.44 |
| Density | 1.190±0.06 g/cm3(Predicted) |
| Boling Point | 573.7±33.0 °C(Predicted) |
| pKa | 3.91±0.21(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD02682634 |
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanoic acid - Risk and Safety
| Hazard Class | IRRITANT |
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanoic acid - Introduction
Fmoc-2-aminoheptanoic acid (Fmoc-2-aminoheptanoic acid) is an organic compound commonly used as an amino-protecting group in solid-phase synthesis.
Fmoc-2-aminoheptanoic acid has the following properties:
-Chemical formula: C19H21NO4
-Molecular weight: 323.38g/mol
-Appearance: White or off-white solid
-Melting Point: 78-81°C
-Solubility: Soluble in some organic solvents, such as dimethylformamide (DMF) and methanol
The main use of Fmoc-2-aminoheptanoic acid is as an amino protecting group in solid phase synthesis. In solid-phase synthesis, it usually reacts with amino acid residues to form protected derivatives of amino acids to protect the amino group and prevent non-specific position reactions from occurring. After the synthesis is complete, the Fmoc protecting group can be removed by basic conditions for subsequent synthetic steps.
The preparation method of Fmoc-2-aminoheptanoic acid is usually obtained by synthesizing a blocking reagent or directly. Synthetic blocking reagents are generally obtained by reacting aminoheptanoic acid with Fmoc-peak propionic acid (Fmoc-phenylalanine) under acid catalysis. The direct acquisition method is to purchase the compound provided by the manufacturer.
For safety information, the specific safety of Fmoc-2-aminoheptanoate should refer to the safety data sheet (SDS) and operating manual of the chemical. In general, it may have an irritating effect on the eyes, respiratory system and skin. Wear appropriate personal protective equipment to avoid contact with skin and eyes. At the same time, it is necessary to wear respiratory protection equipment when used in unventilated conditions or during operation. Chemicals should be stored in a dry, cool, well-ventilated place away from heat sources and flames to prevent contact with incompatible substances. Observe all relevant safety procedures when using.
Fmoc-2-aminoheptanoic acid has the following properties:
-Chemical formula: C19H21NO4
-Molecular weight: 323.38g/mol
-Appearance: White or off-white solid
-Melting Point: 78-81°C
-Solubility: Soluble in some organic solvents, such as dimethylformamide (DMF) and methanol
The main use of Fmoc-2-aminoheptanoic acid is as an amino protecting group in solid phase synthesis. In solid-phase synthesis, it usually reacts with amino acid residues to form protected derivatives of amino acids to protect the amino group and prevent non-specific position reactions from occurring. After the synthesis is complete, the Fmoc protecting group can be removed by basic conditions for subsequent synthetic steps.
The preparation method of Fmoc-2-aminoheptanoic acid is usually obtained by synthesizing a blocking reagent or directly. Synthetic blocking reagents are generally obtained by reacting aminoheptanoic acid with Fmoc-peak propionic acid (Fmoc-phenylalanine) under acid catalysis. The direct acquisition method is to purchase the compound provided by the manufacturer.
For safety information, the specific safety of Fmoc-2-aminoheptanoate should refer to the safety data sheet (SDS) and operating manual of the chemical. In general, it may have an irritating effect on the eyes, respiratory system and skin. Wear appropriate personal protective equipment to avoid contact with skin and eyes. At the same time, it is necessary to wear respiratory protection equipment when used in unventilated conditions or during operation. Chemicals should be stored in a dry, cool, well-ventilated place away from heat sources and flames to prevent contact with incompatible substances. Observe all relevant safety procedures when using.
Last Update：2024-04-10 22:29:15
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